I found this thread after having trouble getting the DVD-RAM drive on my new ThinkPad 
assigned to something other than the D: drive.  Using the aforementioned Computer 
Management applet, I changed the DVD-RAM drive to R:, but it would never survive 
a reboot.  I tried starting up in Safe Mode, but this didn't help.  Then, some direction 
took me to the Device Manager, and I found a system device that was malfunctioning. 
 There was a duplicate of the device that was functioning properly, so I uninstalled 
the malfunctioning one.  Reboot, and voilà!  After the restart, the DVD-RAM drive 
was assigned to R:, and my network share assigned to D:!  I still have to see if 
it will survive a powerdown and restart, but I'm hopeful this solves the problem.

Take-away for others trying to solve this:  Check your Device Manager to see if there 
are any devices that need attention, and resolve them as necessary.

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